I-ADOPT Variable Examples

Your resource for modelled I-ADOPT variables with concepts from different terminologies.

mass-based dose of applied nanomaterial internalised by a specific cell population (or per single cell) -mass per cell area

Correlation of dose and response for nanomaterials toxicity assessment requires information on the amount of the applied dose of nanomaterial that has been internalised by a cell population (or per specific cell) and is dependent on a number of factors including the exposure time, the particle density (i.e., whether settling occurs and thus the distribution of particles in the medium is non-homogeneous affecting the local concentration at the cell surface) etc.

Property:

mass

Object of Interest:

nano-materials

Matrix:

cell

Context Objects:

toxicology